Pain is universal. Whether it stems from a genetic disposition, traumatic experience, or moderate discomfort after engaging in physical activity. Pain and aching are the most common reasons people seek medical treatment. About 40% of adults within the United States suffer with chronic pain according to the CDC and mainstay treatment usually relies on NSAID medications like Advil or aspirin (1). However, many studies have revealed that these medications show no long-term benefits (2). Because of this, many people are turning to topical medication to aid in treating their muscle discomforts and aches, as it offers people progressive and local delivery of safe therapeutic components to the sites of their pains.  

Since ancient times, people have been relying on plants and natural remedies to cure all different types of ailments including muscle and joint pain and even with the turn of the centuries, plants remain a large source of modern medicines. With this in mind and the idea to aid in the pain relief at its source, Flexicure’s Joint & Muscle Rapid Relief Cream aims to provide great assistance to relieving physical soreness and aches with its all-natural formulated topical cream.  

Flexicure’s cream includes 8 natural plant derived ingredients formulated to offer a great experience for joint and muscle pain relief. 

Starting with methylsulfonylmethane (MSM), a sulfur- based nutritional 

supplement found in many fruits, vegetables, grains, and milk as well as in some animal meats. MSM gives the body a good supplement for sulfur which is necessary for the synthesis of certain essential amino acids and therefore has been tested for its therapeutic treatment for exercise soreness. Marathon runners were given MSM supplements or a placebo for three weeks after a run, to see its effects on post-race associated aches, and researchers found that the MSM group had reduced amount of pain compared to the placebo group (3), giving light onto the benefits of MSM as a therapeutic component. 

The second ingredient in Flexicure’s cream is glucosamine, which is an important building block for our cartilage, ligaments, and tendons – which are the sites of creaky joints. In recent studies, glucosamine was shown to reduce the level of pain of osteoarthritic patients and when paired with other vitamins created a great synergistic therapeutic effect against rheumatoid arthritis (RA) (4). Giving the body additions of its own building blocks can supply the body with more artillery to make repairs and fight against pain. 

Salix alba, or willow bark, is a white willow recognized as a great source for salicylic acid, a precursor to one of the most common pain relief medicines, acetylsalicylic acid, or aspirin. Aspirin has many adverse effects like stomach ulcers, blood thinning and hemorrhage which its precursor, Salix alba does not. When combined with other anti-inflammatory interventions, Salix alba, can be a great source for providing assisted relief towards aches (5). 

The eucalyptus oil, a distilled oil made from the leaves of the eucalyptus tree is very versatile in its uses and has been found to have abetting therapeutic effects. The anti-inflammatory and antibacterial characteristics has made it a natural source for giving promise to treating many ailments including arthritis (6). It is found in many soaps, herbicides and even perfumes, and therefore has a strong holding in the realm of aromatherapy. In addition to its natural pain-relieving characteristics, its antibacterial component helps prevent the spread of infections. Therefore, this natural and pleasant-smelling oil is a great additive to Flexicure’s soothing formula. 

A grandmother’s favorite remedy for any cold, headache or ailment is to drink lemon ginger tea.  Zingiber officinale Roscoe or Ginger has its own pain reducing effects through regulating different inhibitory pathways in the body to reduce and even stop certain pains (7).  A full natural ingredient, already a culinary favorite, can provide some beneficial therapeutic effects. 

Next, we have Boswellia, a plant derivative that is recommended in many cases of musculoskeletal inflammation and works by stopping certain pain pathways. Studies have shown some direct therapeutic effects on knee swelling and has increased the walking abilities of many osteoarthritis patients (8). As well, athletes who received Boswellia infused creams for their post exercise soreness reported significant improvements in stiffness and overall mobility that controlled groups (9).

A bit more unfamiliar, Arnica montana, is found in many foods and is classified as a flavonoid. Flavonoids are metabolites and therefore are consumed in our daily diets. In vivo studies performed in the lab across different human cells, traced the immunogenic actions of Arnica montana and observed that it increased white blood cellular activity against inflammations (10). This and other studies show great promise for Arnica montana as a great source for aiding in pain and was another obvious natural component to add to the mix. 

Flexicure’s last ingredient in their formula is Comfrey root, a plant root found in many traditional medicinal plants. Native Americans recognized the great healing powers of this plant and used it a lot in treating many ailments including muscle and joint pains. That’s why modern research is exploring more of Comfrey roots therapeutic components and many randomized and controlled studies have been conducted and demonstrated the beneficial effects and the safety application of comfrey as a topical agent to treat for pain swelling and inflammation of the muscle and joints (11). 

As muscle and joint pain is widely felt across populations globally it is important for the market to meet the demands for proper and efficient long-lasting cures. However, as pain is so common, the market has become oversaturated with many remedies harboring artificial and processed ingredients. Now more than ever, people are more conscious of what they are putting in their bodies and they want to understand and research the ingredients they absorb. That’s why Flexicure has turned to natural pain-relieving ingredients of 6 herbal extracts plus MSM and glucosamine to give people the relief they need with the ingredients they know to be natural and healthy. 

1) https://www.cdc.gov/mmwr/volumes/67/wr/mm6736a2.htm

2) https://pubmed.ncbi.nlm.nih.gov/21386951/

3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595302/

4) https://link.springer.com/article/10.1186/s13568-020-00987-8

5) https://www.sciencedirect.com/science/article/pii/S1319610310000578

6) https://doi.org/10.1002/jsfa.8600 

7) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754412/

8) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747466/

9) https://europepmc.org/article/med/32880419

10) https://www.sciencedirect.com/science/article/abs/pii/S1475491604000098

11) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580139/#CR6

 

Living a healthy lifestyle is a process and requires effort to maintain. The challenge is to find effortless ways to help boost your immune system and promote your overall well-being. Flexicure understands this challenge and formulated naturally processed herbal products that are effortlessly nutritious and delicious. Flexicure’s Natural Anti-inflammatory Beverage Powder offers a unique blend of herbal extracts that support flexible and comfortable joints and boosts a strong immune system while spoiling our taste buds with great natural flavoring. 

Here is more on the benefits of our ingredients:

 The formula starts with Astragalus extract, which comes from the dried root of Astragalus membranaceus, a shrub plant from the legume family. Thought to prolong life and used for thousands of years in Chinese, Astragalus has modernly proven itself to show reduced inflammatory response (1). A clinical study observed that when injected with extract of astragalus, pediatric heart disease patients showed improved immune function (2). Astragalus also has proven antioxidative properties (1). Our bodies can accumulate harmful molecules called free radicals which can cause damage to the DNA of our cells and antioxidants help defend the body against them. 

Flexicure’s next ingredient is also known for its anti-inflammatory and antioxidative properties and is a familiar one to most, Turmeric. A staple spice in Indian cuisine, Turmeric has been used by Indians for far more than just flavoring. For centuries Indians considered Tumeric an effective medicinal plant. That’s because researched revealed turmeric’s active compound called curcumin which gives turmeric its powerful anti-inflammatory effects and is a strong antioxidant itself. Curcumin has been found to improve symptoms of depression and arthritis (3) backing up turmeric’s ancient tradition as a remedy. 

Methylsulfonylmethane (MSM), a nutritional

supplement that serves as a great source for sulfur. It plays a role in anti-inflammation by reducing levels of inflammatory compounds subsequently reducing stress on the immune system. MSM also plays part in glutathione production, which is the body’s coveted antioxidant involved in many important cellular processes the body needs to repair tissue damage and maintain a healthy immune system (4).

The beet juice will help increase your stamina. Beets are full of natural chemicals called nitrates that our body can turn into nitric acid (NO). NO helps to improve blood flow and lowers our blood pressure and this is evident across many studies (5). Beets also offer a great source for potassium, a mineral that can help nerve and muscle function. More recent research has also revealed beets offer potent anti-inflammatory agents and a great component to an anti-inflammatory ingredient.  As an ingredient in Flexicure’s beverage formula, beet juice can boost your energy during the day, while enhancing your immune system. 

Pineapple juice, the next ingredient in Flexicure’s formula, is a great source of vitamins. It contains high amounts of vitamin C, manganese, copper, vitamin B6 and Vitamin A, and these vitamins have antioxidants. Pineapple juice also contains an enzyme called bromelain which has many therapeutic effects. Bromelain helps triggers your body’s ability to fight pain and reduce swelling and is a common remedy for sports injuries and osteoarthritis (6). 

Vitamin C is one of our immune systems greatest friends but a vitamin that our bodies can’t produce on their own. This makes incorporating vitamin C rich foods into our daily diet vital and is why it’s one of Fleixcure’s key components. Vitamin C works to support cell function against pathogens and to repair damaged skin cells after an infection or harm (7). This vitamin is also essential in cellular clearance after an immune attack and helps the body maintain balance and remain healthy. That’s why vitamin C is used as both a preventative and treatment in the clinics for a variety of diseases, (8) and one of the most popular vitamins people take. 

Berries are small yet packed with nutrients, vitamins, and antioxidants. They have the highest content of antioxidants from all foods, with their very high nutrient content (9). They are also low in calories making them a great component of any nutritional diet. Furthermore, they’re a growing interest to clinical researchers as they offer great promising therapeutic effects. One study showed that powdered mixed berries extract is attributed to the apoptosis, or cellular death process, of cancer cells (10), slowing down or even obstructing cancer growth. 

 Citric acid is a well-known ingredient that gives lemons and citrus food their sour taste. But more than just a flavor, citric acid helps convert the food we eat into cellular energy. This is our cell’s holy grail of energy storage and creation, our body’s citric acid cycle. Citric acid also promotes calcium, phosphorus and magnesium in our guts which helps the gut process and digest food (11). 

Stevia is now well mainstream in many favorite food and beverage products and included in many weight-loss programs because of its low-calorie plant. Stevia also has strong naturally sweet taste, making it a staple alternative to sugar. But the potential benefits of stevia have yet to be fully discovered and is starting to be researched for its potential use as an additive treatment to help combat medical conditions such as diabetes, high blood pressure and heartburn (12).

With all their natural benefits, the herbal extracts that make up our Natural Anti-inflammatory Beverage Powder, offer an easy way to add a delicious energizing boost throughout your day while effortlessly working to strengthen and support your immune system. 

 

1. https://www.mdpi.com/1422-0067/19/3/800
2. https://pubmed.ncbi.nlm.nih.gov/25087616/
3. https://altmedrev.com/wp-content/uploads/2019/02/v14-2-141.pdf
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229597/
5. https://pubmed.ncbi.nlm.nih.gov/22248502/
6. https://pubmed.ncbi.nlm.nih.gov/28065968/ 
7. https://pubmed.ncbi.nlm.nih.gov/29099763/
8. https://www.mdpi.com/2072-6643/9/11/1211/htm
9. https://pubs.acs.org/doi/abs/10.1021/jf801381y 
10. https://pubmed.ncbi.nlm.nih.gov/26501271/
11. https://www.ncbi.nlm.nih.gov/books/NBK26882/
12. https://www.cmaj.ca/content/189/28/E929.full 

 

Living with chronic pain is an unfortunate way of life for many individuals. Oftentimes, individuals seek the help and advice of a doctor to help relieve or manage their pain. And if you’ve ever been to the doctor for chronic or nagging pain issues, chances are, you were prescribed a prescription medication or a high dosage of ibuprofen to attack your annoying pain. 

However, when you turn to traditional medications, pain killers, and opiates, you may run the risk of harmful side effects or even addiction. Many individuals would prefer to avoid these adverse effects by turning towards a more natural form of pain relief. But what can you turn to that has been clinically researched and proven to relieve pain naturally?

Contrary to popular belief, there are a number of ways to relieve your pain naturally. These solutions could include herbal supplements, yoga, acupuncture, and natural pain relief creams such as what we’ve created with Flexicure through over 25 years of clinical research and testing. 

Here’s a list of the powerfully effective and 100% natural ingredients contained in Flexicure:

BOSWELLIA SERRATA

The active ingredients of this resin has numerous health benefits, among which include, anti-inflammatory properties. It is said to help in relieving discomfort in bones and joints and possibly improve joint function. Boswellia serrata is also referred to as frankincense and has been used for centuries in Asian and African folk medicine. In addition to its historical uses, Boswellia Serrata is also an effective painkiller and has been useful in treating conditions such as:

• Osteoarthritis
• Rheumatoid arthritis
• Asthma
• Inflammatory bowel disease 

Clinical studies for boswellia serrata have supported its effectiveness in treating and managing pain in patients. Other data suggest that a boswellia based cream helps to prevent skin damage from radiation treatments in breast cancer patients. 

GINGER

When you think of ginger, you think of a spice used to make food or even some desserts. Ginger, however, has many healing properties. This spicy yellow root has been known to alleviate problems related to an upset stomach, the common cold, nausea, and even diarrhea. When taken orally, it has been found to reduce pain associated with osteoarthritis. It’s anti-inflammatory properties are effective in treating issues such as:

• Cancer
• Tumors
• Bacterial infection
• Migraines
• Diabetes
• Ulcers

When used topically, ginger has been shown to be effective at improving mobility, decreasing inflammation and reducing pain. In a double-blind study of 50 patients located in Thailand, research showed that topical use of ginger was effective in relieving pain and increasing mobility among the study group. 

SALIX ALBA

This species of willow bark is said to ease aches and pains and reduce fevers. Referred to as a natural aspirin, this bark is said to relieve pain associated with headaches, muscle pain, menstrual cramps, and rheumatoid arthritis. The ingredients salicin are said to have similar properties to aspirin which is effective for pain relief. There are studies that show that salix alba can cause slight weight loss. While weight loss may be a favorable result for many, the main feature of this bark is treating fever and relieving pain. Other uses date back to ancient Egyptian and Greek times when this ingredient was used topically for joint discomfort and inflammation. The Ingredient salicin has been approved by the Food and Drug Administration in the treatment of calluses and warts. This ingredient has also been known to treat the following:

• Bunions
• Corns
• Acne

Because of the potency of this ingredient, it has become a main ingredient for many topical creams. 

COMFREY SYMPHYTUM

Comfrey symphytum has been referred to as “knitbone” due to its unique ability to heal broken bones. It’s been said that this natural ingredient can knit bones back together. It aids in speeding up the healing process and can heal wounds and bruises. When used as a natural pain relief cream, it helps in reducing inflammation and alleviating pain. It is helpful for the following problems:

• Bruises
• Fractures
• Sprains
• Gout

When used on a daily basis, comfrey can alleviate pain associated with back pain, ankle sprains and osteoarthritis. There have been numerous clinical studies to support this natural ingredient’s ability to relieve the pain associated with arthritis. Comfrey has been used in traditional medicine for centuries. This medicinal plant is commonly found throughout Europe and some parts of Asia.

MSM (Methylsulfonylmethane)

Often used to treat arthritis, MSM can be taken orally or topically to relieve pain and swelling associated with osteoarthritis and tendonitis. When used topically it can treat inflammation and discoloration. This organic treatment is helpful in unclogging pores and is considered a better alternative to harsh chemicals for treating acne. MSM acts as a glue in our bodies helping to build our tissues. Topical uses also help with collagen production which results in a reduction of wrinkles. It soothes itching and reduces scar tissue. This natural ingredient helps internally with the following:

• Nasal allergies
• Boosts concentration
• Enhances energy

The sulfur properties are also beneficial for your hair, skin and nails. Clinical studies have shown that the use of MSM decreases pain and function impairment. Studies support improved performance of daily activities among a population of 50 men and women from ages 40 to 76 years of age. 

GLUCOSAMINE

Glucosamine is the cartilage builder that helps relieve joint pain swelling and stiffness. It is considered an alternative for the treatment of osteoarthritis. Glucosamine is found in the fluid surrounding our joints and reduces joint pain and stiffness. It is also good for minimizing cartilage loss for individuals suffering from osteoarthritis. This naturally occurring substance enhances healing after sprains and slows the effect of aging on the joints. Studies of glucosamine have shown that it may inhibit the breakdown of cartilage and is absorbed into the system within a matter of hours. When used topically, it can improve your skin. Some topical benefits include:

• Wound healing
• Skin hydration
• Wrinkle reduction

Glucosamine has antioxidant and anti-inflammatory properties that help to counteract free radicals of the skin cells. 

ARNICA

This herbal plant extract is available in forms such as gels, creams, and tablets. Arnica grows mainly in Siberia and central Europe. It is used for bleeding, bruising and post surgery swelling. Arnica’s active chemical acts as an antibiotic. Research shows that consistent use of this herb in topical form reduces stiffness and pain and improves function of hands and knees with people suffering from osteoarthritis. Referred to as mountain daisy, this herb can be used topically or as a tincture. Regardless of the use, it is great in treating the following conditions:

• Bruises
• Sprains
• Muscle pain
• Joint pain

By mixing an arnica tincture with a small amount of purified water and dipping the solution onto a gauze pad, it can be used in the form of a compress to relieve musculoskeletal pain. Modern clinical research shows arnica to be just as effective as ibuprofen and when compared to ibuprofen showed a higher reduction in pain intensity and an increase in hand function. Arnica’s natural pain relief can be a formidable alternative to ibuprofen. 

Conclusion

While prescription drugs can help you get a quick hit of relief, they can wreak havoc in other ways. With this being such a serious concern for many patients, there is no wonder people are opting for natural alternatives. Prescription medications are not the only culprits. Over the counter pain relievers have also been known to have a detrimental effect. One example is aspirin. Even though aspirin has been recommended to help reduce the risk of heart attack and stroke, it can cause problems to your digestive system such as nausea and vomiting. 

It is becoming more evident for individuals battling pain that over the counter and prescription drugs are a less preferred method. Flexicure is an all natural topical pain reliever that penetrates deep into your tissues and can alleviate the need for over the counter pain relievers. If you’re interested in a natural solution for pain, visit our website to review our 100% all-natural pain cream.